The movement to 'go local' is the opposite of big-box shopping. The rise of the conscious consumer and the desire to support local products and brands has helped to increase small business revenue.
Local business generates 70% more local economic activity per square foot than big box retail. So selling locally produced products not only helps you, but it can help the broader economy of your community.
You don't have to sell items. If that doesn't work well for your store, consider to showcase and integrate locally-made items into your interior.